It’s certainly true that observation plays a crucial role in science. But this doesn’t mean that scientific theories have to deal exclusively in observable things. For one, the line between the observable and unobservable is blurry – what was once ‘unobservable’ can become ‘observable’, as the neutrino shows. Sometimes, a theory that postulates the imperceptible has proven to be the right theory, and is accepted as correct long before anyone devises a way to see those things.