People can be skeptical or distrusting of science for different reasons, whether it is about one specific finding from one discipline (for example, ‘The climate is not warming, but I believe in evolution’), or about science in general (‘Science is just one of many opinions’). We identified four major predictors of science acceptance and science skepticism: political ideology; religiosity; morality; and knowledge about science. These variables tend to intercorrelate – in some cases quite strongly – which means that they are potentially confounded.